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<body topmargin=0 leftmargin=0 marginheight=0 marginwidth=0> <table cellpadding=0 cellspacing=0 border=0><tr> <td valign="top" colspan=2 height=22 BGCOLOR="#FFFFFF" TEXT="#080000" bgproperties="fixed" background="041000d2egerdp.gif"> <div> </div> </td> </tr><tr> <td valign="top" width=145 BGCOLOR="#333399" TEXT="#080000" background="040a2c00erkjzj.gif"> <div>  <img src="HTMLobj-524/aniGif.gif" border="0" align="bottom" width="100" height="76">  </div> </td> <td valign="top" height=458 BGCOLOR="#FFFFFF" TEXT="#080000"> <div> <FONT SIZE="5" COLOR="#336600" FACE="Times New Roman" ><I>TUMORS</I></FONT><FONT SIZE="1" COLOR="#663399" FACE="Times New Roman" >    </FONT> |    <B> </B><FONT SIZE="2" COLOR="#0000BF" FACE="Times New Roman" ><A HREF="index.htm" TARGET="_top" TITLE="TUMORS"><U><B>home</B></U></A></FONT></div> <div> <A HREF="id17.htm" TARGET="_top" TITLE="generality and definition"><U>generality and definition</U></A>   |   <A HREF="id63.htm" TARGET="_top" TITLE="chart"><U>chart</U></A>   |   <A HREF="id22.htm" TARGET="_top" TITLE="diag and treatment"><U>diag and treatment</U></A>   |   <A HREF="id18.htm" TARGET="_top" TITLE="specificity"><U>specificity</U></A>   |   <B>pictures</B>   |   <A HREF="id23.htm" TARGET="_top" TITLE="cancer by organ"><U>cancer by organ</U></A>   |   <A HREF="id24.htm" TARGET="_top" TITLE="My Photos"><U>My Photos</U></A>   |   <A HREF="id20.htm" TARGET="_top" TITLE="Related Links"><U>Related Links</U></A>   |   <A HREF="id21.htm" TARGET="_top" TITLE="Contact Me"><U>Contact Me</U></A></div> <div> <IMG SRC="04207040.gif" border=0 width="263" height="4" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></div> <div> <B>pictures</B></div> <div> <IMG SRC="07ac22d0.jpg" border=0 width="450" height="301" ALIGN="BOTTOM" HSPACE="0" VSPACE="0">villous adenoma bladder<IMG SRC="07bc22d0.jpg" border=0 width="450" height="301" ALIGN="BOTTOM" HSPACE="0" VSPACE="0">http://www.afip.org/cgi-bin/edu/coursepage.pl?code=1&id=4</div> <bR> <div> <IMG SRC="07dce2c0.gif" border=0 width="462" height="300" ALIGN="BOTTOM" HSPACE="0" VSPACE="0">http://edcenter.med.cornell.edu/CUMC_PathNotes/Neoplasia/45.GIF</div> <div> <B>Invasive squamous cell carcinoma of bladder (with keratin pearls) </B></div> <div> Tumor cells invade the smooth muscle of the bladder wall (center) and are arranged in concentric masses of keratin-producing cells or keratin pearls. </div> <div> <IMG SRC="1fde0ef0.jpg" border=0 width="736" height="495" ALIGN="BOTTOM" HSPACE="0" VSPACE="0">BREAST CANCER [ED LULO.MD[Malignant glands. </div> <div> What features of anaplasia are present? </div> <div> <IMG BORDER="0" SRC="Symb075c00b700f000000000.gif" HEIGHT="16" WIDTH="24" ALIGN="bottom" HSPACE="0" VSPACE="0">Pleomorphism (cells of varying size and shape)</div> <div> <IMG BORDER="0" SRC="Symb075c00b700f000000000.gif" HEIGHT="16" WIDTH="24" ALIGN="bottom" HSPACE="0" VSPACE="0">The nuclei of the tumor cells are larger and darker than normal cells, including the ones in the connective tissue of the tumor;</div> <div> <IMG BORDER="0" SRC="Symb075c00b700f000000000.gif" HEIGHT="16" WIDTH="24" ALIGN="bottom" HSPACE="0" VSPACE="0">The glands are irregular]http://uhsweb.edu/~lulo/gallery.htm</div> <bR> <div> THE FOLLOWING PICTURES ARE FROM DR.ED .FREIDLANDER</div> <div> MY PERSONAL COLLECTION WILL BE ON A SPECIAL CHAPTER PICTURES TUMORS </div> <div> THE LINK WILL BE ON MY MAIN PATHOLOGY PAGE : <A HREF="HTTP://PATHOLOGYLECTURES.HOMESTEAD.COM" TARGET="_top" TITLE="HTTP://PATHOLOGYLECTURES.HOMESTEAD.COM"><U>HTTP://PATHOLOGYLECTURES.HOMESTEAD.COM</U></A></div> <div> <IMG SRC="07e58930.jpg" border=0 width="600" height="403" ALIGN="BOTTOM" HSPACE="0" VSPACE="0">lymphoma</div> <div> <IMG SRC="07f58890.jpg" border=0 width="600" height="393" ALIGN="BOTTOM" HSPACE="0" VSPACE="0">all</div> <div> <IMG SRC="08058860.jpg" border=0 width="600" height="390" ALIGN="BOTTOM" HSPACE="0" VSPACE="0">lymphosarcoma</div> <div> <IMG SRC="081588d0.jpg" border=0 width="600" height="397" ALIGN="BOTTOM" HSPACE="0" VSPACE="0">lymphomyeloma</div> <div> <IMG SRC="08258930.jpg" border=0 width="600" height="403" ALIGN="BOTTOM" HSPACE="0" VSPACE="0">hodgkin's</div> <div> <IMG SRC="0838a580.jpg" border=0 width="394" height="600" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></div> <div> <IMG SRC="08458970.jpg" border=0 width="600" height="407" ALIGN="BOTTOM" HSPACE="0" VSPACE="0">signet cell</div> <div> <IMG SRC="085a2580.jpg" border=0 width="418" height="600" ALIGN="BOTTOM" HSPACE="0" VSPACE="0">lymphoma</div> <div> <IMG SRC="08658880.jpg" border=0 width="600" height="392" ALIGN="BOTTOM" HSPACE="0" VSPACE="0">reed stenberg</div> <div> <IMG SRC="087588d0.jpg" border=0 width="600" height="397" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></div> <div> <IMG SRC="08858910.jpg" border=0 width="600" height="401" ALIGN="BOTTOM" HSPACE="0" VSPACE="0">hodgkin spleen</div> <div> <IMG SRC="089588c0.jpg" border=0 width="600" height="396" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></div> <div> <IMG SRC="08a58810.jpg" border=0 width="600" height="385" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></div> <div> hodgkin's</div> <div> <IMG SRC="08b58970.jpg" border=0 width="600" height="407" ALIGN="BOTTOM" HSPACE="0" VSPACE="0">cml</div> <div> <IMG SRC="08c589a0.jpg" border=0 width="600" height="410" ALIGN="BOTTOM" HSPACE="0" VSPACE="0">myeloma</div> <div> <IMG SRC="08d58820.jpg" border=0 width="600" height="386" ALIGN="BOTTOM" HSPACE="0" VSPACE="0">leukemia</div> <div> <IMG SRC="08e90580.jpg" border=0 width="400" height="600" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"><IMG SRC="20b42860.jpg" border=0 width="578" height="390" ALIGN="BOTTOM" HSPACE="0" VSPACE="0">KIDNEY KC [ED <IMG SRC="20df4470.jpg" border=0 width="500" height="327" ALIGN="BOTTOM" HSPACE="0" VSPACE="0">LULO.MD]<FONT SIZE="3" COLOR="#000000" FACE="Arial" >This is at high magnigication. Notice the large Keratin Pearl (looks like pink ribbon swirling in a circle) characteristic finding in squamous cell cancer. Also, notice that the nuclear:cytoplasmic ratio is increased. (Normal is 3:1). Called squamous because of the similarity to fish scales. (skin) </FONT></div> <div> <IMG SRC="1fe20580.jpg" border=0 width="800" height="600" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></div> </td> </tr></table></body>