"Appare" means "Bravo", "Zipangu" (Jipangu) is the name (meaning "land of gold") that Marco Polo gave to Japan. 

Yusura was left underneath a cherry tree as a baby with the Kongoumaru by her side. 15 years later she's become the Hikeshiya (the extinguisher of sorrow) by using the Kongoumaru which turn's blue as it absorbs people's sorrows then sends it back to the person guilty of causing the sorrow. 

Be sure to heed the following warning found at the beginning of the manga: 

"This book is not cold medicine. If it is taken by mistake please rinse with water immediately and consult a doctor. When using, please read the explanatory note on handling and use correctly. It will be the cause of accidents." 

(I swear, I didn't make that up! It really was in the manga!)